The disappearance of Flight 370 isn't just weighing on the families of these passengers.
It's also causing the surviving family members of other plane crashes to re-live their own tragedies.
CNN's Kyung Lah spoke to a woman whose father's plane vanished more than 60 years ago – but still can't find the closure she needs.
Darlene Larson was just 5 years old when her father, Leo, boarded Northwest Orient Flight 2501 at La Guardia Airport on June 23, 1950.
He was flying home to Minneapolis but never made it. The DC-4 plane with 58 passengers crashed into Lake Michigan, becoming at that time, the worst commercial aviation disaster in U.S. history.
The fuselage and engine never foundâ€” the only remnants discovered were a few body parts.
Larson says she was awoken by her mother crying, do her best to tell her that her father "would not be coming back."
"It's a hard concept because you don't have anything to hold onto," Larson said. "Like a funeral, a casket, or a grave. I was certain he was wandering around Chicago with amnesia and would realize where he was and would come home."