Italy's Supreme Court wants Amanda Knox, the former American exchange student, to stand trial again for murder.
Knox spent four years in jail for the 2007 murder of her roommate – who prosecutors claim was killed after a drug fueled sex game gone wrong.
That verdict was overturned by an appeals court in 2011, and Knox returned home to the U.S.
So will Amanda Knox be heading back to Italy and jail?
OutFront tonight: Former prosecutor Wendy Murphy and criminal defense attorney Anne Bremner.