More than a foot of wind whipped snow is expected to fall and that snow will be accompanied by an arctic blast of subzero temperatures in some areas.
To the north - Boston and Cape Cod are expected to bear the brunt of this nor'easter. By this time Friday, people there could be digging out of 18 inches of snow.
Nor'easter forming off the East Coast predicted to bring blizzard conditions
The weather is also having a ripple effect at many of the nation's airports. Already more than 2,000 flights have been canceled.
This fast moving nor'easter is also challenging some of the nation's newly minted mayors. In New York – this is the first test for Mayor Bill de Blasio's administration and Boston's next mayor, who takes office Monday, will face the daunting task of dealing with the storm's clean-up.
And as we have seen time and time again - these storms can make or break a political career.
CNN's Don Lemon reports.
Georgia police have arrested a former banker suspected of faking his own death in 2012. He had been accused of embezzling millions from investors.
Georgia banker who allegedly embezzled $17 million captured after years on lam
Aubrey Lee Davis was captured Tuesday after spending a year and a half on the run and made his first court appearance today.
CNN's David Mattingly has the story.
Police have arrested a man suspected of killing a beloved Catholic priest.
Gary Lee Bullock was taken into custody and charged with the murder of Pastor Eric Freed.
Beloved Catholic priest found slain in California church rectory
The 56-year-old priest was found dead inside the rectory at St. Bernard Church on Wednesday after he failed to show up to morning mass.
William Herbrechtsmeier, who has known Reverend Freed for the past seven years and taught with him at Humboldt State University, is OutFront.
The controversy over Duck Dynasty patriarch Phil Robertson's anti-gay comments doesn't appear to be slowing down the family's business.
"Duck Dynasty" launches its own line of guns
Gunmaker Mossberg has announced that it will be launching a "Duck Dynasty" line of guns.
OutFront: Aaron smith of CNN Money.
Colorado made history this week, with retail pot dispensaries selling recreational marijuana for the first time.
Colorado's recreational marijuana stores make history
Residents across the state are celebrating, but Colorado law enforcement officials worry that the new law could bring a host of unexpected problems.
Miguel Marquez has more on the story.