Amanda Knox is defiant she's not going back to prison.
"I will never go willingly back to the place where I... I'm gonna fight this until the very end," Knox said on ABC's "Good Morning America."
Knox spoke out after an Italian court found her and her ex-boyfriend, Raffaele Sollecito, guilty of murder for the second time in four years.
Knox learned the news while at home in Seattle, but Sollecito is still in Italy and was actually stopped by police late last night in a small town near the Slovenian border.
His attorney says he was not trying to flee but was driving to his girlfriend's hometown. Sollecito voluntarily turned over his passport.
The former couple was convicted in 2009 of killing Knox's British roommate, Meredith Kercher, in what prosecutors described as a sex game gone wrong. The case made headlines around the world as tabloids dubbed the American exchange student "foxy knoxy."
Knox spent four years in an Italian prison but was freed in 2011 after an appeals court overturned the guilty verdict citing a lack of evidence.
The reversal in 2011 was another stunning twist in the case and the world watched as Knox returned home to her family. That's where she says she watched her third trial unfold in disbelief.
"This really has hit me like a train," Knox says. "I did not expect this to happen. I really expected so much better from the Italian justice system. They found me innocent before. How can they say that it's guilt beyond a reasonable doubt?"
The guilty verdict is little consolation to Meredith Kercher's family. After nearly seven years of controversial evidence and testimony, they say they may never know the truth.
"Nothing will bring Meredith back and nothing will take away the horror of what happened to her," Lyle Kercher says. "The best we can hope for is to finally bring this case to a conclusion and then everybody can move on with their lives."
But with one more appeal to Italy's highest court, a final conclusion may still be years away, and Amanda Knox is vowing to continue the fight.
"There are people who know better than I do the way these systems work, and the way that there was this entirely preventable thing that happened that was the system and i really hope that people try to understand that like when you have overzealous prosecutors and when you have a biased interrogation - biased investigation and coercive interrogations like these happened and I'm not crazy," Knox says.
Outfront: Steve Moore is a former FBI special agent who wrote a book about the Knox case, and CNN legal analyst and former homicide prosecutor, Paul Callan.