Nancy Writebol, an aid worker in Liberia, was helping treat Ebola patients until she tested positive for the virus herself - the second American so far.
This comes just days after another American, Dr. Kent Brantly also became infected while treating Ebola patients.
Second American infected with Ebola
The current outbreak is the deadliest ever, so far claiming hundreds of lives.
And many more people could be infected and not even know it yet. One man boarded a flight last week not knowing he had Ebola. But days later, he died. His flight included stops in three countries.
CNN's Erin Burnett speaks with Ken Isaacs, Vice President of Samaritan's Purse, an organization the two Americans are affiliated with - about their current condition.
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Way to go Erin & CNN for allowing your guest Ken Isaacs to minimize one of the most contagious and deadly diseases of the 21st Century, the Ebola Virus. You did not cover how exactly this is spread and if other passengers may have been exposed to it or if the airplane needs to be decontaminated. Or the fact that not everyone can be screened for flu like symptoms but how about just the people that have been in contact with patients having the disease? If your just going to use a powder puff to deliver the news what good is your Upfront Journalism?